The Real Truth: Antidepressants Actually Deplete These 3 Crucial Nutrients For the Brain

In this article, we will share the experience of Jordan Fallis, a brain health journalist, and biohacker about the antidepressants. According to him, by managing symptoms with synthetic man-made drugs, you will make to feel better for a while, but if you stop those drugs, your symptoms can even increase.

His personal experience was the following:

–           When he took antidepressants, he felt better initially

–           Then, he felt something going in a wrong way

–           He started suffering from cognitive decline, which was something new for him

–           He was fed up with the medication and tried getting off them.

–           Then, he noticed worsening of the conditions, much worse than he did before starting the medication.

–           The explanation of the doctors was that he is experiencing a decline in his depression and anxiety.

–           However, that was not true, because not only were his symptoms much worse, but he got a few new symptoms

–           After some research he did, he discovered something that is called “drug-induced nutrient depletion”.

That means that pharmaceutical drugs can deplete the body of critical nutrients through multiple mechanisms, such as impaired digestion and absorption, increased excretion of nutrients, and storage of nutrients. These deficiencies of nutrition can even develop after some time. As a result of deficiencies, the people can suffer from additional symptoms and increase side effects.

Usually, these additional symptoms and “side effects” are diagnosed as a new disease, so you should take new drugs that further deplete nutrients.

Here you can find the explanation about the three key nutrients that are commonly depleted by psychiatric medication, which will not be noticed in the drug package or by your doctor.

  1. Coenzyme Q10 (CoQ10)

This is a molecule that exists in every cell of your body and its responsibility is to produce the energy.

As a powerful antioxidant, it protects your body and brain from free radical damage. When the levels of CoQ10 increase it has a significant antidepressant effect, which is experimented in rats.

Unfortunately, most of the studies show that a number of psychiatric medications (antidepressants and antipsychotics) deplete CoQ10. In such cases, when the levels of CoQ10 are low it can cause brain fog, difficulty concentrating, mental fatigue, memory lapses, irritability and deepen the depression.

  1. Magnesium

As a vital mineral, magnesium participates in more than 300 biochemical reactions in your body, such as a neurotransmitter, hormonal activity, and enzyme, and has a huge effect on your mood and brain function.

Magnesium is one of the most important nutrients for optimal brain health, which helps in reducing anxiety, irritability, and depression. As a result of magnesium deficiency, many people experience the following symptoms:

–           Increased blood pressure

–           Headaches and migraines

–           Muscle weakness, tremors, cramps, and spasms

–           Insomnia

–           Heart arrhythmias

–           Suicidal thoughts

–           Nausea

–           Osteoporosis

Interestingly, these symptoms sound very similar to the list of side effects of some psychiatric medications.

So, in case of mental health condition, or taking medication to deal with it, the magnesium level should be considered. Furthermore, you should consume lots of food with magnesium (avocados, pumpkin seeds, almonds, swiss chard, dark chocolate, spinach, halibut, and beets).

  1. B Vitamins

By taking psychiatric medication you can deplete a number of B vitamins (B2, B6, B12, and folate), too.

The deficiency of Vitamin B2 can affect the entire body, leading to low energy, weight gain, and thyroid and skin problems. Mood stabilizers, antipsychotics, antidepressants and can obstruct the absorption of vitamin B2. Because of that your need for supplementation increases.

So, you should take healthy food sources of riboflavin, such as pastured eggs, leafy vegetables, mushrooms, beef liver, almonds and sunflower seeds.

Vitamin B6 also supports your entire nervous system, boosts mood, deepens sleep, as it is responsible for the production of many neurotransmitters in your brains, such as serotonin, GABA, and dopamine.

The deficiency of Vitamin 6 causes weakness, depression, mental confusion, insomnia and severe PMS symptoms.

Include in your diet the best sources of the vitamin B6, such potatoes, bananas, and chicken.

Vitamin B12 and folate

They are essential B vitamins that play a key role in methylation, the process that proves your body and brain optimal energy and nervous system function.

One of the very often reason for depression is exactly the lower level of B12 and folate.  However, many doctors instead of looking at folate and B12 levels in the blood, they often prescribe antidepressants, antipsychotics, anticonvulsants, benzodiazepines and mood stabilizers, which on the other hand can deplete folate and B12.

The deficiency of B12 and folate leads to increased homocysteine levels, which can worsen your depression, fatigue, irritability, forgetfulness, and confusion.

Dietary sources of natural folate are leafy greens, broccoli, asparagus, strawberries, and cauliflower.


The medication taken for mental health can actually reduce nutrients essential for your body and brain (vitamins and minerals), which can lead to unwanted side effects and declining health.

In order to avoid these side effects, and even control and overcome chronic mental disease without medication, you can restore these missing nutrients.


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